keeps plague bacteria from infecting the immune system
14% of Eames, England's population today.
Mutant gene blocks white blood cells from being undermined
by infective bacteria
1 copy of the gene slows infection
2 copies of the gene do not get an
The base sequences of DNA that
code for proteins because of how the sequences are arranged on the
double helix wrapped tightly within the chromosomes are called genes.
But they are wrapped tightly around histones that package the chromosomal material and only certain proteins can unravel that tightly knotted section of the nucleotide.
These base pair sequences are the actual chemical
components of what biologists call, the "genotype."
Evelyn Fox Keller, in The Century of the Gene, refers to this physical
and chemical manifestation of order as having "particulate materiality."
Clearly genes, or so Keller argues, are more than
codes for making proteins. They are complex expressions (phenotype)
of the underlying material (genotype) processes and instructional guidelines
mediated by proteins and RNA in the nuclei and cytoplasm of cells.
• Thus the closer we get to observing genes the less clearly they
• For genes are not just pieces that as blueprints, dictate or prescribe the outcome (phenotypic expression of underlying genotype).