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Themes are like threads folded in a story's plots.
A theme in Darwin's story of natural selection is
Survival of the fortunate, is a more sensible, defensible and less uncertain interpretation of Darwin's descent by means of natural selection, given what we do know today of genetics, selection ecology and paleontology.
Frankengenes have become one hysterical reaction to the biological revolution called "genetic engineering," that has also swept up stem cell research into the fears the public expresses over radical new techniques in medicine, therapy and agricultural genetics.
"The Unseen Genome: Beyond DNA" genetic vs. epigenetic considerations are discussed here.